What is wrong with my Burnet Saxifrage (Pimpinella saxifraga)?

Are the leaves covered with white powder?

Are the leaves pale on their upper side and are there any dusty blisters on the undersides?

Do the leaves have large, ragged holes in them?

Are the leaves curled and yellow?

White, powdery patches on the leaves are caused by a fungal disease Powdery mildew. Powdery mildew usually appears in damp places. Encourage good air circulation around the affected plants by thining them and any surrounding plants. Water plants from below to keep foliage dry. Any affected leaves should be cut off and removed. The appropriate fungicidal spray will protect your plant from further infections.

Likely cause for these symptoms is a fungal disease - Rust. Provide good air circulation around plants by thining them. Avoid making leaves wet when watering. All infected leaves should be removed. Spray leaves with sulfur early in the season to prevent rust or to treat mild infections.

Large, ragged holes in the leaves are caused by slugs and snails. Slugs and snails feed on the plant leaves usually at night. To control slugs and snails use diatomaceous earth around your plants. You can also handpick them during the night or use shallow dishes filled with beer as a trap.

Distorted, curled leaves are caused by aphids. These tiny insects cluster under leaves and on growing tips where they feed on plant sap. Leaves, stems, and buds get distorted, and later leaves and flowers drop from the plant. You can control them by washing them off the plant with water spray. Insecticidal soap should be used with severe infestations.

Mineral deficiencies can cause tip chlorosis or necrosis or cause foliage to discolor, fade, distort, or become spotted, sometimes in a characteristic pattern that can be recognized to identify the cause. When nutrient deficiencies occur, nitrogen and iron are the most commonly seen deficiencies. Apply only the mineral found to be deficient. Excess nutrients, on the other hand, cause symptoms like leaf tip dieback, marginal leaf chlorosis, necrosis (or burn), branch dieback, and pest problems. In this case, you should provide good drainage, and use good practices during fertilization and irrigation.